PC-LINKERS™
AmberGen has developed and patented a novel class of photocleavable linkers (PC-Linkers™) and related methods that are helping to pioneer novel applications in the Life Sciences. Applications developed by AmberGen include photo-printing of microarrays, photocleavable mass-tags for coding ultra-high density bead-arrays and photocleavable affinity agents for biomarker purification. These reagents have been licensed for use with other companies’ products such as the SomaLogic® SOMAScan® multiplex proteomic biomarker assay.
- Fast Photocleavge in Seconds
- Efficiencies >95%
- Low Intensity Near-UV Light
Trademarks: SomaLogic®, SOMAmer® and SOMAscan® are registered trademarks of SomaLogic, Inc.
PC-PURE™
AmberGen’s patented photo-affinity based biomarker purification technology (PC-PURE™) provides dramatic improvements in today’s newer generation of multiplex diagnostic assays by eliminating the matrix effect.
Miralys™ Photocleavable Mass-tag Tissue Imaging Probes
Mass spectrometric color image of human tonsil tissue produced using highly multiplex MALDI-IHC.
The mass spectrum shown is a superposition of spectra from seven selected pixels in the image.
A New Technology for Spatial Biology Imaging
▶ Multiplex. Capable of 100+ biomarkers. Single scan, no cycling. Every probe has a unique tag.
▶ Multimodal. One sample → results from many imaging modalities.
▶ Multiomic. One workflow→ Small molecules, intact proteins and other macromolecules, and glycosylation.
▶ Easy Workflow. No conjugation. One staining step. No metal tags.
▶ Familiar Methods. Leverages traditional MSI and IHC methods and equipment.
▶ Fast. Image entire slide in 40 min. Drill down to ROIs at higher res.
▶ Reliable Platform. Developed using mass spectrometers from Bruker.