Ambergen

Photocleavable Linkers
Figure 2: The Use of Ambergen's PC-Amino Modifier Phosphoramidite.

Figure 2: The Use of Ambergen's PC-Amino Modifier Phosphoramidite.

The reagent can be coupled to the 5' end of an oligonucleotide using standard chemistries. The free 5' primary amine can then be reacted with any marker (M), which can be a solid surface (e.g. NHS activated beads) or another compound (e.g. standard NHS activated fluorophores and affinity tags). Photocleavage separates the marker from the oligonucleotide.

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