Miralys™ Photocleavable Mass-tag Tissue Imaging Probes
Mass spectrometric color image of human tonsil tissue produced using highly multiplex MALDI-IHC.
The mass spectrum shown is a superposition of spectra from seven selected pixels in the image.
A New Technology for Spatial Biology Imaging
▶ Multiplex. Capable of 100+ biomarkers. Single scan, no cycling. Every probe has a unique tag.
▶ Multimodal. One sample → results from many imaging modalities.
▶ Multiomic. One workflow→ Small molecules, intact proteins and other macromolecules, and glycosylation.
▶ Easy Workflow. No conjugation. One staining step. No metal tags.
▶ Familiar Methods. Leverages traditional MSI and IHC methods and equipment.
▶ Fast. Image entire slide in 40 min. Drill down to ROIs at higher res.
▶ Reliable Platform. Developed using mass spectrometers from Bruker.