AmberGen Papers
Highly Multiplexed Immunohistochemical MALDI-MS Imaging of Biomarkers in Tissues
Gargey Yagnik, Ziying Liu, Kenneth J. Rothschild*, and Mark J. Lim*
Publication Date: February 25, 2021
https://doi.org/10.1021/jasms.0c00473
Proteome-wide drug screening using mass spectrometric imaging of bead-arrays.
Zhou Y, Liu Z, Rothschild KJ, Lim MJ.
Sci Rep. 2016 May 19;6:26125. doi: 10.1038/srep26125.
PMID:27194112 Free PMC Article
Correlated matrix-assisted laser desorption/ionization mass spectrometry and fluorescent imaging of photocleavable peptide-coded random bead-arrays.
Lim MJ, Liu Z, Braunschweiger KI, Awad A, Rothschild KJ.
Rapid Commun Mass Spectrom. 2014 Jan 15;28(1):49-62. doi: 10.1002/rcm.6754.
PMID:24285390 Free PMC Article
Multiplexed VeraCode bead-based serological immunoassay for colorectal cancer.
Ostendorff HP, Awad A, Braunschweiger KI, Liu Z, Wan Z, Rothschild KJ, Lim MJ.
J Immunol Methods. 2013 Dec 31;400-401:58-69. doi: 10.1016/j.jim.2013.09.013. Epub 2013 Oct 24.
PMID: 24161315 Free PMC Article
An ELISA-based high throughput protein truncation test for inherited breast cancer.
Lim MJ, Foster GJ, Gite S, Ostendorff HP, Narod S, Rothschild KJ.
Breast Cancer Res. 2010;12(5):R78. doi: 10.1186/bcr2722. Epub 2010 Oct 4.
PMID: 20920338 Free PMC Article
Photocleavage-based affinity purification and printing of cell-free expressed proteins: application to proteome microarrays.
Lim M, Rothschild KJ.
Anal Biochem. 2008 Dec 1;383(1):103-15. doi: 10.1016/j.ab.2008.07.038. Epub 2008 Aug 12.
PMID: 18762158 Free PMC Article
Cell-free protein synthesis systems: biotechnological applications.
Gite S, Lim M, Rothschild KJ.
Biotechnol Genet Eng Rev. 2006;22:151-69. Review. No abstract available.
PMID: 18476330
N-terminal labeling of proteins using initiator tRNA.
Olejnik J, Gite S, Mamaev S, Rothschild KJ.
Methods. 2005 Jul;36(3):252-60.
PMID: 16076451
Cell-free N-terminal protein labeling using initiator suppressor tRNA.
Mamaev S, Olejnik J, Olejnik EK, Rothschild KJ.
Anal Biochem. 2004 Mar 1;326(1):25-32.
PMID: 14769332
Fluorescent in situ sequencing on polymerase colonies.
Mitra RD, Shendure J, Olejnik J, Edyta-Krzymanska-Olejnik, Church GM.
Anal Biochem. 2003 Sep 1;320(1):55-65. Erratum in: Anal Biochem. 2004 May 15;328(2):245.
PMID: 12895469
A high-throughput nonisotopic protein truncation test.
Gite S, Lim M, Carlson R, Olejnik J, Zehnbauer B, Rothschild K.
Nat Biotechnol. 2003 Feb;21(2):194-7. Epub 2003 Jan 13. Erratum in: Nat Biotechnol. 2003 Sep;21(9):1098.
PMID: 12524552
Photochemical control of the infectivity of adenoviral vectors using a novel photocleavable biotinylation reagent.
Pandori MW, Hobson DA, Olejnik J, Krzymanska-Olejnik E, Rothschild KJ, Palmer AA, Phillips TJ, Sano T.
Chem Biol. 2002 May;9(5):567-73.
PMID: 12031663 Free Article
Matrix-assisted laser desorption/ionization mass spectrometry of DNA using photocleavable biotin.
Hahner S, Olejnik J, Lüdemann HC, Krzymañska-Olejnik E, Hillenkamp F, Rothschild KJ.
Biomol Eng. 1999 Dec 31;16(1-4):127-33.
PMID: 10796995
Ultrasensitive fluorescence-based detection of nascent proteins in gels.
Gite S, Mamaev S, Olejnik J, Rothschild K.
Anal Biochem. 2000 Mar 15;279(2):218-25.
PMID: 10706791
Photocleavable peptide-DNA conjugates: synthesis and applications to DNA analysis using MALDI-MS.
Olejnik J, Lüdemann HC, Krzymanska-Olejnik E, Berkenkamp S, Hillenkamp F, Rothschild KJ.
Nucleic Acids Res. 1999 Dec 1;27(23):4626-31.
PMID: 10556319 Free PMC Article
Photocleavable aminotag phosphoramidites for 5′-termini DNA/RNA labeling.
Olejnik J, Krzymanska-Olejnik E, Rothschild KJ.
Nucleic Acids Res. 1998 Aug 1;26(15):3572-6.
PMID: 9671821 Free PMC Article
Photocleavable affinity tags for isolation and detection of biomolecules.
Olejnik J, Krzymañska-Olejnik E, Rothschild KJ.
Methods Enzymol. 1998;291:135-54. No abstract available.
PMID: 9661149
Photocleavable biotin phosphoramidite for 5′-end-labeling, affinity purification and phosphorylation of synthetic oligonucleotides.
Olejnik J, Krzymańska-Olejnik E, Rothschild KJ.
Nucleic Acids Res. 1996 Jan 15;24(2):361-6.
PMID: 8628663 Free PMC Article
Photocleavable biotin derivatives: a versatile approach for the isolation of biomolecules.
Olejnik J, Sonar S, Krzymañska-Olejnik E, Rothschild KJ.
Proc Natl Acad Sci U S A. 1995 Aug 1;92(16):7590-4.
PMID: 7638235 Free PMC Article
The Power of AmberGen Technology
Chemically modified DNA aptamers bind interleukin-6 with high affinity and inhibit signaling by blocking its interaction with interleukin-6 receptor.
Gupta S, Hirota M, Waugh SM, Murakami I, Suzuki T, Muraguchi M, Shibamori M, Ishikawa Y, Jarvis TC, Carter JD, Zhang C, Gawande B, Vrkljan M, Janjic N, Schneider DJ.
J Biol Chem. 2014 Mar 21;289(12):8706-19. doi: 10.1074/jbc.M113.532580. Epub 2014 Jan 12.
PMID: 24415766 Free PMC Article
Enrichment and site mapping of O-linked N-acetylglucosamine by a combination of chemical/enzymatic tagging, photochemical cleavage, and electron transfer dissociation mass spectrometry.
Wang Z, Udeshi ND, O’Malley M, Shabanowitz J, Hunt DF, Hart GW.
Mol Cell Proteomics. 2010 Jan;9(1):153-60. doi: 10.1074/mcp.M900268-MCP200. Epub 2009 Aug 19.
PMID: 19692427 Free PMC Article
Fluorescent in situ sequencing on polymerase colonies.
Mitra RD, Shendure J, Olejnik J, Edyta-Krzymanska-Olejnik, Church GM.
Anal Biochem. 2003 Sep 1;320(1):55-65. Erratum in: Anal Biochem. 2004 May 15;328(2):245.
PMID: 12895469
Single-stranded antisense siRNAs guide target RNA cleavage in RNAi.
Martinez J, Patkaniowska A, Urlaub H, Lührmann R, Tuschl T.
Cell. 2002 Sep 6;110(5):563-74.
PMID: 12230974 Free Article
Photochemical control of the infectivity of adenoviral vectors using a novel photocleavable biotinylation reagent.
Pandori MW, Hobson DA, Olejnik J, Krzymanska-Olejnik E, Rothschild KJ, Palmer AA, Phillips TJ, Sano T.
Chem Biol. 2002 May;9(5):567-73.
PMID: 12031663 Free Article
Coupled transcription and translation within nuclei of mammalian cells.
Iborra FJ, Jackson DA, Cook PR.
Science. 2001 Aug 10;293(5532):1139-42. Epub 2001 Jun 21.
PMID: 11423616 Free Article
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